Bhullar et al, 2014: antiseizure prophylaxis after TBI

Journal Club 013

Authors: Vanessa Phua, Chris Nickson and Andrew Udy

Bhullar IS, Johnson D, Paul JP, Kerwin AJ, Tepas JJ 3rd, Frykberg ER. More harm than good: antiseizure prophylaxis after traumatic brain injury does not decrease seizure rates but may inhibit functional recovery. J Trauma Acute Care Surg. 2014 Jan;76(1):54-60; discussion 60-1. doi: 10.1097/TA.0b013e3182aafd15. PubMed PMID:24368357.

The Alfred ICU Journal Club Review of this article was published by the Winnower here. It is open for post-publication peer review, and will be embedded in this webpage once it is archived.

[/color-box]

References and Links

  • LITFL CCC — Post-Traumatic Seizures
  • Szaflarski JP et al. Prospective, randomized, single blinded comparative trial of intravenous levetiracetam versus phenytoin for seizure prophylaxis. Neurocrit Care 2010;12:165-172. PubMed PMID: 19898966

Leave a Reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.