Sepsis and Septic Shock SDL

Alfred ICU Guidelines – available via PROMPT

• Antimicrobials in ICU
• Sepsis Care Bundle Guideline
• Blood Culture Collection in Adults, Paediatrics and Neonates Guideline

Surviving Sepsis Guidelines

• 2021 Surviving Sepsis Guidelines

LITFL CCC Entries

• Sepsis overview
• Sepsis definitions and diagnosis
• Fluid bolus therapy
• Fluid responsiveness
• Noradrenaline
• Vasopressin
• Central venous oxygen saturation (ScvO2) monitoring
• Lactate clearance vs ScvO2 monitoring in severe sepsis

Other information (particularly useful for CICM trainees)

• McGloughlin on The Dying Traveller (2014 smaccGOLD talk on sepsis in travellers by Steve McGloughlin)
• Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med. 2013 Aug 29;369(9):840-51. doi: 10.1056/NEJMra1208623. Review. Erratum in: N Engl J Med. 2013 Nov 21;369(21):2069. PubMed PMID: 23984731. [Free Full Text]
• Marik PE. Early management of severe sepsis: concepts and controversies. Chest. 2014 Jun;145(6):1407-18. doi: 10.1378/chest.13-2104. PubMed PMID: 24889440. [Free Full Text]
• Infectious diseases and Microbiology SDL (INTENSIVE)
• See the Deranged Physiology Fellowship exam question bank for relevant past questions on these topics.